Home › Wegovy pill › Side effects
Wegovy pill side effects
About this page. Written by the GLPInfo editorial team with AI assistance from the official sources listed at the end, and approved by the site owner before publication. It has not been reviewed by a named clinician. Published 27 Aug 2026 · last updated 27 Aug 2026 · next scheduled review 27 Nov 2026.
This page is information, not medical advice. It never tells you which medicine, dose or format is right for you: those decisions sit with you and a qualified prescriber. Spotted an error? Tell us and we'll fix it fast.
This page summarises how the patient information leaflet categorises Wegovy pill's side effects. It is deliberately unsoftened: the leaflet in your pack is the authority, your prescriber assesses your personal risk, and Report suspected side effects through the MHRA Yellow Card scheme.
Common effects
The tablet carries semaglutide's profile: nausea, diarrhoea, vomiting, constipation, abdominal pain and reduced appetite are the most commonly reported effects, worst around dose increases. Because the medicine is the same as the injection, the leaflet's side-effect list closely mirrors the injectable Wegovy leaflet.
Serious risks
The serious risks mirror the injection too: acute pancreatitis, gallbladder disease, dehydration from persistent vomiting or diarrhoea, allergic reactions, and retinopathy considerations in type 2 diabetes. Severe, persistent abdominal pain needs urgent attention.
Worth knowing
One tablet-specific note: gastrointestinal effects can make the strict fasting routine harder to keep, and a routine that slips reduces absorption. If side effects are disrupting how you take it, tell your prescriber rather than improvising: how to take the Wegovy pill. Not for use in pregnancy, with the same two-month pre-pregnancy stop advice as the injection.
Managing the common effects
Practical, NHS-guidance-level measures for nausea, constipation and dehydration, plus the red flags that mean stop self-managing and call, are collected in one place: managing GLP-1 side effects. Always tell your prescriber what you are experiencing; dose timing and step-ups are their levers, not yours.
Related: what is Wegovy pill? · how to take Wegovy pill · dose schedule
Frequently asked questions
Do Wegovy pill side effects go away?
The common gastrointestinal effects are typically worst after starting or increasing a dose and ease as the body adjusts, which is exactly why doses climb slowly. Effects that are severe, persistent or worrying belong with your prescriber, not with waiting. Practical self-care measures are covered in managing GLP-1 side effects.
When should I seek urgent help?
Severe persistent abdominal pain (with or without vomiting), signs of an allergic reaction such as swelling of the face or throat or difficulty breathing, or signs of serious dehydration all need urgent medical attention: 999 or A&E for the emergencies, NHS 111 when unsure.
Should I report side effects even if they are listed?
Yes. Reporting through the MHRA Yellow Card scheme strengthens the safety picture for everyone, and reporting something does not require certainty that the medicine caused it.