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Medicine profile

Amycretin

Investigational single-molecule GLP-1 and amylin agonist in subcutaneous and oral formulations; results are formulation-specific.

Generic name
Amycretin
Also known as
NNC0487-0111
Sponsor and licensing
Novo Nordisk (originator)
Mechanism
GLP-1 and amylin receptor agonist (single molecule)
Molecular type
Peptide (mechanism and molecular type are recorded separately: GLP-1 activity does not make a medicine a peptide)

Brands, routes and formulations

Amycretin (no brand yet)

subcutaneous 路 once-weekly injection

No verified approval recorded for this product.

Amycretin (no brand yet)

oral 路 once-daily tablet

No verified approval recorded for this product.

Regulatory status by jurisdiction

Authorisation, launch and funded access are three different things and are shown separately. "Not recorded" means GLPInfo has not verified an event, not that nothing has happened.

United States (FDA)United Kingdom (MHRA)European Union (EMA / EC)
Regulatory authorisationNot recordedNot recordedNot recorded
Commercial launchNot recordedNot recordedNot recorded
Funded accessNot recordedNot recordedNot recorded

Development timeline

Amycretin

Novo Nordisk 路 GLP-1 and amylin receptor agonist (single molecule) 路 Peptide 路 Investigational
Region
20262027202820292030
USFDA
TodayNo verified events yet
UKMHRA
No verified events yet
EUEMA / European Commission
No verified events yet

No verified events recorded yet.

Confirmed eventCompany targetRegulator targetEditorial estimateTiming unknown or undatedSafety update

Dashed line: today, 13 Sep 2026. Future windows are conditional. Approval, launch and funded access are separate milestones.

Select a marker to open its record in the pipeline view, which has the detail panel and the accessible list.

Next milestone and forecast rationale

No forecast is published for Amycretin. One appears only when there is a responsible range with assumptions and sources.

Trial evidence

TrialPhasePopulationDurationResults
Amycretin subcutaneous phase 1b/2a (obesity)Novo Nordisk 路 subcutaneous, once weekly (dose escalation up to 60 mg)1b/2aAdults with overweight or obesity (BMI 27 or more) without diabetes; the workbook's 125-participant figure is unverified36 weeksOn file from the research workbook; withheld until the primary publication or registry record is attached.

GLPInfo does not rank unrelated trials against each other or quote "weight loss per week": populations, durations and methods differ and weight change is not linear. Results appear here per trial and dose arm, with comparator, endpoint and source, once cited.

Known limitations and official labels

This profile is assembled from the regulatory records and sponsor statements GLPInfo has verified; it is not a complete review of Amycretin. The current official label in each jurisdiction is the authority on indications, populations and safety.

Review date and correction history

Records last checked 13 Sep 2026. No corrections have been made to the records on this profile; every record is at version 1. Report a correction.

Related news

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